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Diagnosis and Treatment of Benign Prostatic Hyperplasia in Dogs: New Approaches

Derakhshandeh N, Mogheiseh A, Nazifi S

Veterinary medicine international, 2025

Abstract

This review aims to define the best prescription options for the treatment and diagnosis of benign prostatic hyperplasia (BPH) in dogs. BPH has become the most common disease in older dogs. While it rarely poses life-threatening risks, it can significantly impact a patient's quality of life, as changes in prostate size can lead to various clinical signs, including tenesmus, constipation, and hematuria. An accurate initial evaluation and diagnostic method are essential for distinguishing BPH from other conditions and differential diagnoses. Treatment modalities include both medical and surgical options. In recent years, medical therapy for BPH has expanded and improved. The focus of medical treatment is to reduce prostatic volume, alleviate bothersome clinical sign, and prevent the need for surgical intervention, especially for dogs that are still used for breeding. The pharmacological effects, efficacy, and safety of these treatments must be thoroughly analyzed to ensure good drug adherence and persistence.

How strong is the evidence?

Evidence Hub reads this as a review, done in animal, not in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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