Brucella orchitis: A case report on a rare cause of scrotal abscess leading to orchiectomy
Abstract
Brucellosis, a zoonotic infection common in Iran, rarely causes genitourinary complications such as orchitis. We report a 65-year-old Persian cattle farmer with brucellosis who developed a testicular abscess despite antibiotic therapy. Initial treatment with rifampin and doxycycline resolved systemic symptoms, but scrotal pain prompted ultrasound, revealing a right testicular abscess. Orchiectomy was performed due to extensive necrosis, with histopathology confirming necrotizing brucellar orchitis. Post-surgical levofloxacin and clindamycin prevented recurrence at six months. This case highlights the need to consider Brucella orchitis in endemic regions when scrotal pathology persists, as advanced cases may require surgical intervention.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Ferulic acid regulates the AKT/GSK-3β/CRMP-2 signaling pathway in a middle cerebral artery occlusion animal model
- Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure–Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant Escherichia coli
- Photochemical behavior of levofloxacin
- Correlation Between Dissolution Profiles of Salt-Form Drugs in Biorelevant Bicarbonate Buffer and Oral Drug Absorption: Importance of Dose/ Fluid Volume Ratio
- Evaluation of the synergistic potential and mechanisms of action for de novo designed cationic antimicrobial peptides
- Synthesis of [11C]levofloxacin
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.