Refractory granulomatous lobular mastitis associated with subpectoral abscess and localized Salmonella infection: A case report
Abstract
We report a rare granulomatous lobular mastitis (GLM) associated with Salmonella spp. infection in a 41-year-old woman presenting as a subpectoral abscess. Diagnosis was delayed due to negative routine cultures and atypical presentation. Surgical excision combined with long-term levofloxacin therapy achieved full recovery. Effective treatment requires antimicrobial coverage and elimination of static secretions in the mammary gland to prevent recurrence. Our case presents a unique perspective by illustrating how Salmonella, a facultative intracellular pathogen that targets macrophages and other immune cells, may secondarily infect a GLM lesion, characterized by dense infiltration of immune cells.
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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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