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β-Cyclodextrin/carbon dots-grafted cellulose nanofibrils hydrogel for enhanced adsorption and fluorescence detection of levofloxacin

Yuting Zhang, Xinmiao Qi, Xuefeng Zhang, Yong Huang, Qiang Ma, Xin Guo, Yiqiang Wu

Carbohydrate Polymers, 2024

33 citations

Abstract

In this study, a novel hydrogel, β-cyclodextrin/carbon dots-grafted cellulose nanofibrils hydrogel (βCCH), was fabricated for removal and fluorescence determination of levofloxacin (LEV). A comprehensive analysis was performed to characterize its physicochemical properties. Batch adsorption experiments were conducted, revealing that βCCH reached a maximum adsorption capacity of 1376.9 mg/g, consistent with both Langmuir and pseudo-second-order models, suggesting that the adsorption process of LEV on βCCH was primarily driven by chemical adsorption. The removal efficiency of βCCH was 99.2 % under the fixed conditions (pH: 6, initial concentration: 20 mg/L, contact time: 300 min, temperature: 25 °C). The removal efficiency of βCCH for LEV still achieved 97.3 % after five adsorption-desorption cycles. By using βCCH as a fluorescent probe for LEV, a fast and sensitive method was established with linear ranges of 1-120 mg/L and 0.2-1.0 μg/L and a limit of detection (LOD) as low as 0.09 μg/L. The viability of βCCH was estimated based on the economic analysis of the synthesis process and the removal of LEV, demonstrating that βCCH was more cost-effective than commercial activated carbon. This study provides a novel approach for preparing a promising antibiotic detection and adsorption material with the advantages of stability, and cost-effectiveness.

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