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Left atrial appendage closure in patients with atrial fibrillation: grey zones involving trials, meta-analysis, and decision-making

G. F. Romiti, B. Corica, G. Boriani

Europace, 2026

Abstract

This editorial refers to ‘Long-Term Efficacy and Safety of Left Atrial Appendage Closure Versus Oral Anticoagulation in Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials, by P. Karakasis et al. , https://doi.org/10.1093/europace/ euag159 and ‘Comparative Evaluation of Left Atrial Appendage Occlusion And Oral Anticoagulation: A Bayesian Meta-Analysis of Randomized Controlled Trials’, by K. S. Athmakuri et al. , https://doi.org/10.1093/europace/euag163

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