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Engaging rural communities in Bangladesh to address antimicrobial resistance via the community dialogue approach: a protocol for a cluster-randomized controlled trial

Rebecca King, J. Hicks, F. Fieroze, Md Badruddin Saify, S. Abdullah, D. Barrington, P. Hamade, Helen Hawkings et al.

Frontiers in Public Health, 2025

2,200 participants

Abstract

Introduction To effectively tackle antibiotic resistance (ABR) a One Health approach is required, focusing on the human, animal and environmental sectors together, and that public education and engagement programs must be part of the overall approach. However, there has been limited research on such programs in low−/middle-income countries (LMICs). Here we describe our plans to evaluate a community-engagement program, known as the community dialogue approach, that takes a One Health approach to tackling ABR in rural communities in Bangladesh, and involves community-led and community-based education and discussion forums. Members of our team previously developed this approach and used it to address other health issues in other LMIC contexts, while our team has previously adapted it for this topic and setting. Methods We will use a pragmatic, non-blinded, two-arm, parallel-group, cluster-randomized, controlled trial to primarily evaluate whether the intervention can improve (1) the level of correct and appropriate knowledge about antibiotics, ABR, and antibiotic usage from a One Health perspective, (2) levels of awareness about the existence of antibiotics and ABR, and (3) the relative frequency of self-reported and observable indicators of best practices related to antibiotic usage. Within Cumilla district, we will randomize 50 clusters of villages in a 1:1 ratio. In intervention community clusters trained community volunteers will deliver a set of 11 health education and…

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 2,200 participants or records.

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