Platelet-rich Plasma and Its Application in Clinical Trial
Abstract
Platelet-rich plasma (PRP) is an autologous physiological product that has a platelet concentration above baseline. The PRP contains a high level of important growth factors and cytokines such as PDGF, EGF, VEGF, TGF-β,... which play important roles in healing and tissue regeneration. The PRP is currently used in various medical fields, including orthopedic, plastic surgery, dermatology, dentistry, musculoskeletal and obstetrics-gynecology. To date, the results from in vitro, in vivo studies to clinical trials have proved the effectiveness of PRP in the treating of many diseases. Altogether, PRP is considered to be a very promising futuristic therapy by dint of its simple and highly potential clinical application.
Keywords: Platelet-rich plasma, PRP, growth factors, applications of platelet-rich plasma.
References
[1] J. S. F. Moure, J. L. V. Eps, F. J. Cabrera, Z. Barbosa, G. M. D. Rosal, B. K. Weiner, et al., Platelet-rich Plasma: A Biomimetic Approach to Enhancement of Surgical Wound Healing, Journal of Surgical Research, Vol. 207, No., 2017, pp. 33-44, https://doi.org/10.1016/j.jss.2016.08.063.[2] A. Zarbock, R. K. P. Grabowska, K. Ley, Platelet-neutrophil-interactions: Linking Hemostasis and Inflammation, Blood Reviews, Vol. 21, No. 2, 2007, pp. 99-111, https://doi.org/10.1016/j.blre.2006.06.001.[3] R. E. Marx, Platelet-rich Plasma (PRP): what is PRP and what is not PRP?, Implant Dentistry, Vol. 10, No. 4, 2001, pp. 225-228,…
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