Chemometric profiling of metabolites in Avicennia marina leaves from various locations in Indonesia
Abstract
Abstract. Saputri FHD, Susanto E, Sabdaningsih A. 2026. Chemometric profiling of metabolites in Avicennia marina leaves from various locations in Indonesia. Biodiversitas 27 (1): d270139. https://doi.org/10.13057/biodiv/d270139. Avicennia marina is a mangrove species that thrives in extreme environments and produces various metabolites. This study analyzes variation in the secondary metabolite profiles of A. marina leaf extracts collected from three Indonesian locations: Cilacap, Pontianak, and Sangihe. The total phenolic and flavonoid content, antioxidant activity, and metabolite profiles were assessed using spectrophotometric assays and Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS). Chemometric analyses were performed using Principal Component Analysis (PCA) and partial least squares discriminant analysis. The results showed that ethyl acetate leaf extracts of A. marina from Sangihe exhibited the highest levels of phenolics (13.811 mg GAE/g), flavonoids (76.179 mg QE/g), and antioxidant activity (0.556 µg/mL, 0.249 µg/mL, and 0.232 µg/mL) using three different methods. LC-HRMS detected 618 metabolite compounds. PCA showed clear clustering patterns among the sample groups, with two principal components: PC1, which explained variation by extraction technique, and PC2, which explained variation across ecological and genetic regions. These results indicate that environmental conditions and solvent types influence the type of metabolite compounds. Specific…
Read the paper
Related studies
- In silico strategies for modeling RNA aptamers and predicting binding sites of their molecular targets
- Folic acid-hydrophilic polymer coated mesoporous silica nanoparticles target doxorubicin delivery
- Anti-phytopathogenic and plant growth promoting potential of endophytic fungi isolated from Dysoxylum gotadhora
- Mercury toxicity causes iron and sulfur deficiencies along with oxidative injuries in alfalfa (Medicago sativa)
- Suppression of lncRNA GAS6-AS2 alleviates sepsis-related acute kidney injury through regulating the miR-136-5p/OXSR1 axis in vitro and in vivo
- Assessing the Protective Effect of Moringa oleifera Extract against Bone Metastasis: An In Vitro Simulated Digestion Approach
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.