Association of Short-Term Exposure to Air Pollution with Depression in Patients with Asthma: A Cross-Sectional Study in Delhi, India
Abstract
Background: Patients with asthma are a population at risk for depression and subsequent mental health risks. Previous studies have suggested that exposure to air pollution is associated with lower asthma control and a higher risk of depression. There is limited evidence on the effect of short-term exposure to air pollution on mental health in susceptible populations, such as patients with asthma. Objectives: The objective of the present study was to assess the association between short-term exposure (≤30d) to air pollution and depression in patients with asthma. Methods: This hospital-based cross-sectional study included 151 consecutively recruited 18- to 65-y-old patients with asthma from two sites in Delhi, India. The Asthma Control Test and the Patient Health Questionnaire-9 were respectively used to assess asthma control and depression status. Data on particulate matter [PM ≤10 and 2.5μm in aerodynamic diameter (PM10 and PM2.5, respectively)], nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide (CO), and ozone (O3) were procured from Central Pollution Control Board (CPCB) air quality monitors, and 1-month average exposures were computed using inverse distance weighting (IDW) based on participant residence and workplace address. Ordinal and binary logistic regressions were respectively used to assess the associations for depression status and asthma control with per-unit interquartile range (IQR) increase of air pollution exposure. Sensitivity analyses were…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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