Evidence Hub

Octreotide for gastrointestinal bleeding in hereditary hemorrhagic telangiectasia: A prospective case series

S. Kroon, R. Snijder, J. Mager, M. Post, Jacco Tenthof van Noorden, E. V. van Geenen, J. Drenth, K. Grooteman

American journal of hematology/oncology, 2019

13 citations

Abstract

axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial. Lancet Oncol. 2019;20(1):31-42. 3. Nastoupil LJ, Jain MD, Spiegel JY, et al. Axicabtagene ciloleucel (axicel) CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed/ refractory large B-cell lymphoma: real world experience. Blood. 2018; 132:91. doi: https://doi.org/10.1182/blood-2018-99-114152 4. Ruella M, Xu J, Barrett DM, et al. Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell. Nat Med. 2018;24(10):1499-1503. 5. Shah NN, Stetler-Stevenson M, Yuan CM, et al. Minimal residual disease negative complete remissions following anti-CD22 chimeric antigen receptor (CAR) in children and young adults with relapsed/refractory acute lymphoblastic leukemia (ALL). Blood. 2016;128(22):650. 6. Mossner E, Brunker P, Moser S, et al. Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity. Blood. 2010;115(22):4393-4402.

How strong is the evidence?

Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free