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Abstract #976395: Case Series: COVID-19 Infection Causing New-Onset Diabetes Mellitus?

Narasa Madam, Rujuta Katkar

Endocrine Practice, 2021

8 participants

Abstract

976395 Case Series: COVID-19 Infection Causing New-Onset Diabetes Mellitus? Author Block: Narasa Madam, MD Co author, Yuma Regional Medical Center; Rujuta Katkar, MD Presenter, Yuma Regional Medical Center Introduction: There is a bidirectional relationship between COVID19 and diabetes. Not only diabetes is associated with an increased risk of severe COVID-19 but also new-onset diabetes and severe metabolic complications of preexisting diabetes, including diabetic ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19. This paper seeks to explore the hypothesis of the S26 potential diabetogenic effect of SARS-COV-2 (Severe Acute respiratory syndrome coronavirus). Case Description:We present a case series of observations among 8 patients of age group ranging from 34 to 74 years with a BMI range of 26.61 to 53.21 Kilogram/square meters that developed newonset diabetes after COVID-19 infection. There was no past medical history of diabetes, pre-diabetes in our patients as evidenced by lab work/Hba1c done prior to hospitalization by their primary care doctors. At admission, they were diagnosed to have COVID-19 based on PCR testing. All patients had severe COVID-19 infection (defined by requiring nasal cannula oxygen therapy of more than 3litres/minute to maintain pulse saturation above 93%), which warranted their admission to the hospital. Initial random blood glucose levels in the basic…

How strong is the evidence?

Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 8 participants or records.

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