624. The influence of psychiatric comorbidity on the level of adherence to psychopharmacotherapy in patients with bipolar disorder
Abstract
Abstract Background The most promising way to improve public health is a strategy to increase adherence to treatment, even compared to efforts to create and develop new effective treatments [1]. Patients with bipolar disorder (BD) often have low levels of adherence to treatment, which has been demonstrated in numerous studies using various assessment methods [2, 3, 4, 5, 6, 7]. Aims & Objectives To identify influence of psychiatric comorbidity on the level of adherence to psychopharmacotherapy in patients with bipolar disorder. Method 106 inpatients diagnosed with BD were examined. Inclusion criteria were: diagnosis of BD according to ICD-10 criteria; previously prescribed pharmacotherapy for BD; age from 18 to 65 years; patient consent to participate in the study and patient’s compliance with therapy. Exclusion criteria: primary patient seeking psychiatric care; pregnancy; dementia; schizophrenia. Evaluation of adherence to therapy was comprehensive: clinical interviews; anamnestic data from people who knew the patient well; determination of the concentration of normothymic medication in the blood. In the study group, women constituted 56.6% (n=60), men 43.4% (n=46). The median age of male patients was 34 [29; 41] years, and of female patients was 32 [25; 48] years. Results In the study group, 59 patients (55.7%) had another mental disorder in addition to BD: alcohol dependence, anxiety spectrum disorders, personality disorder. An assessment of the level of adherence taking…
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