Clinical characteristics and antibiotic susceptibility patterns of bacterial keratitis in the South of Vietnam
Abstract
BACKGROUND: Infectious keratitis is a major cause of corneal blindness, with bacterial keratitis particularly prevalent in tropical, agriculture-dominant regions such as Southern Vietnam.
PURPOSES: To identify the demographic characteristics, risk factors, clinical features, and antibiotic susceptibility patterns of bacteria isolated from patients with corneal ulceration.
METHODS: A case series was conducted involving patients who presented to the Cornea Department of Ho Chi Minh City Eye Hospital between November 2020 and October 2021.
RESULTS: A total of ninety-nine cases of bacterial keratitis were documented. The mean age of the patients was 48.2 ± 15.3 years. Most participants were male, and the majority were cultivators (30.3%). Meibomian gland dysfunction was the most frequent predisposing factor (57.6%), followed by ocular trauma (52.5%) and diabetes mellitus (16.2%). The mean duration from symptom onset to presentation was 4.1 ± 3.1 days; however, patients with Pseudomonas aeruginosa keratitis presented significantly earlier (2.8 ± 1.6 days) than those with other bacterial infections. The most commonly isolated organisms were coagulase-negative Staphylococcus (57.6%) and Pseudomonas aeruginosa (21.2%). Staphylococcus spp. keratitis was significantly associated with peripheral infiltration, shallow stromal involvement, and absence of hypopyon. In contrast, Pseudomonas aeruginosa keratitis was strongly associated with eyelid edema, conjunctival edema, central…
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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