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P-901. Characterizing Changes in Antibiotic Use in the Outpatient Setting – United States, 2019 and 2022

Christine Kim, Tessa C Schwarze, Lauri A. Hicks, Adam L. Hersh, S. Kabbani, Emily McDonald

Open Forum Infectious Diseases, 2026

19 participants

Abstract

Abstract Background Unnecessary antibiotic use is common in outpatient settings, particularly for acute respiratory illnesses. Monitoring antibiotic prescribing and appropriateness is important for identifying stewardship priorities and tracking progress toward national goals. We evaluated changes in outpatient antibiotic prescribing practices and estimated proportions of unnecessary prescribing.Figure 1. Proportion of outpatient visits with an antibiotic prescription by tier* and age group, Merative MarketScan (<65 years) and CMS Medicare (≥65 years) data, 2019 and 2022. *Tier 1 antibiotics are indicated; including pneumonia, urinary tract infection, and miscellaneous bacterial infection. Tier 2 antibiotics are sometimes indicated; including pharyngitis, sinusitis, suppurative otitis media, non-bacterial pneumonia, acute exacerbation of chronic bronchitis, gastrointestinal infection, skin/mucosal infection, and acne. Tier 3 antibiotics are not indicated; including asthma/allergy, bronchitis/bronchiolitis, non-suppurative otitis media, viral upper respiratory infection, COVID-19, respiratory syncytial virus, miscellaneous non-bacterial infection, and fever. †Total of tier 1, tier2, and tier 3 diagnoses.Figure 2. Rate of outpatient visits with an antibiotic prescription by tier* and age group, Merative MarketScan (<65 years) and CMS Medicare (≥65 years) data, 2022. *Tier 1 antibiotics are indicated; including pneumonia, urinary tract infection, and miscellaneous bacterial…

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