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The time is ripe to harmonize global acute febrile illness etiologic investigations

José Moreira, B. Leticia Fernando-Carballo, Camille Escadafal, Sabine Dittrich, Patrícia Brasil, André Machado Siqueira

medRxiv, 2022

Abstract

Abstract We investigated the impact of considering different case definitions of fever as inclusion criteria among participants enrolling in an acute febrile illness investigation and observed that adopting a subjective assessment of fever regardless of specific fever cut-off value accounted for the diversity of clinical fever phenotypes and did not mischaracterize the febrile population.

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