Acute Klebsiella pneumoniae infection of the knee joint following anterior cruciate ligament reconstruction in a young adult: A case report
Abstract
Acute postoperative infection caused by Klebsiella pneumoniae after anterior cruciate ligament reconstruction in young, immunocompetent individuals is exceedingly uncommon. An immunocompetent man in his early 20s developed fever and progressive swelling of the knee 5 days after anterior cruciate ligament reconstruction. Laboratory evaluation demonstrated markedly elevated inflammatory markers, including a C-reactive protein level of 18.36 mg/dL and synovial fluid white blood cell count of 62,667/mm3. Culture of aspirated synovial fluid confirmed infection with Klebsiella pneumoniae, establishing a diagnosis of acute postoperative septic arthritis of the knee. The patient underwent prompt arthroscopic debridement with biofilm debulking. Empirical intravenous piperacillin-tazobactam was administered for 3 days, followed by targeted intravenous levofloxacin for 5 days, and oral levofloxacin to complete an 8-week antimicrobial course. Infection was successfully controlled without graft or implant removal. The patient exhibited clinical improvement with resolution of fever and inflammatory signs following treatment. This case highlights that acute Klebsiella pneumoniae infection of the knee joint can occur even in young, immunocompetent patients shortly after anterior cruciate ligament reconstruction, without an identifiable remote infectious focus. Early recognition, prompt arthroscopic intervention, minimal implant burden, and appropriate targeted antibiotic therapy may enable…
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.