Risk factors for preoperative deep venous thrombosis in hip fracture patients: a meta-analysis
Abstract
Study design A meta-analysis. Background Hip fracture (HF), as common geriatric fracture, is related to increased disability and mortality. Preoperative deep vein thrombosis (DVT) is one of the most common complications in patients with hip fractures, affecting 8–34.9% of hip fracture patients. The study aimed to assess the risk factors of preoperative DVT after hip fractures by meta-analysis. Methods An extensive search of the literature was performed in the English databases of PubMed, Embase, and the Cochrane Library; and the Chinese databases of CNKI and WAN FANG. We collected possible predictors of preoperative DVT from included studies, and data analysis was conducted with RevMan 5.3 and STATA 12.0. Results A total of 26 English articles were included, and the rate of DVT was 16.6% (1627 of 9823 patients) in our study. Our findings showed that advanced age [ p = 0.0003, OR = 0.13 95% CI (0.06, 0.21)], female patients [ p = 0.0009, OR = 0.82 95% CI (0.72, 0.92)], high-energy injury [ p = 0.009, OR = 0.58 95% CI (0.38, 0.87)], prolonged time from injury to admission [ p < 0.00001, OR = 0.54 95% CI (0.44, 0.65)], prolonged time from injury to surgery [ p < 0.00001, OR = 2.06, 95% CI (1.40, 2.72)], hemoglobin [ p < 0.00001, OR = − 0.32 95% CI (− 0.43, − 0.21)], coronary heart disease [ p = 0.006, OR = 1.25 95% CI (1.07, 1.47)], dementia [ p = 0.02, OR = 1.72 95% CI (1.1, 2.67)], liver and kidney diseases [ p = 0.02, OR = 1.91 95% CI (1.12, 3.25)], pulmonary disease [ p =…
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Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 1,627 participants or records.
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