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Reconstruction Kernel Optimization for Ultra-High-Resolution Photon-Counting Detector Computed Tomography of the Lung

Tóth A, Chamberlin JH, Smith CD, Maisuria D, McGuire AM, Schoepf UJ, O'Doherty J, Munden RF et al.

Journal of computer assisted tomography, 2024

25 participants

Abstract

BACKGROUND: The latest generation of computed tomography (CT) systems based on photon-counting detector promises significant improvements in several clinical applications, including chest imaging.

PURPOSE: The aim of the study is to evaluate the image quality of ultra-high-resolution (UHR) photon-counting detector CT (PCD-CT) of the lung using four sharp reconstruction kernels.

MATERIAL AND METHODS: This retrospective study included 25 patients (11 women and 14 men; median age, 71 years) who underwent unenhanced chest CT from April to May 2023. Images were acquired in UHR mode on a clinical dual-source PCD-CT scanner and reconstructed with four sharp kernels (Bl64, Br76, Br84, Br96). Quantitative image analysis included the measurement of image noise, and the calculation of signal-to-noise ratio, and contrast-to-noise ratio. Two radiologists independently rated the images on a 5-point Likert scale for image sharpness, image noise, overall image quality, and airway details. The 4 image sets were compared pairwise in the statistical analysis.

RESULTS: Image noise was lowest for Br76 (74.16 ± 22.05, P < 0.001). Signal-to-noise ratio was significantly higher in the Br76 images (13.34 ± 3.47), than in the other 3 image sets (all P < 0.001). The Br76 images demonstrated the highest contrast-to-noise ratio among all reconstructions (1.54 ± 0.86, all P < 0.001). Subjective image sharpness, image noise, overall image quality, and airway detail were best in the Br76 images (all P <…

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 25 participants or records.

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