Post-Heart Transplant Changes and Perceived Donor-Recipient Correspondences: A Scoping Review
Abstract
Background/Objectives: Heart transplantation is a life-saving treatment for advanced cardiac disease, but post-transplant adaptation may involve psychosocial, identity-related, and existential change. Some recipients interpret these changes as corresponding to donor characteristics, although the nature and evidence base of these reports remain unclear. This review mapped post-transplant changes reported by adult heart transplant recipients, perceived donor-recipient correspondences, and the explanatory frameworks proposed for these phenomena. Methods: A scoping review was conducted following the Arksey and O'Malley framework, Joanna Briggs Institute guidance, and PRISMA-ScR reporting standards. PubMed, Web of Science, Scopus, CINAHL, and PsychINFO were searched in August 2026. Quantitative, qualitative, mixed-methods, conceptual, opinion, and review articles were eligible. Findings were synthesized descriptively. Results: Sixteen sources published between 1992 and 2025 were included. Empirical studies reported changes in preferences, emotional and personality-related experiences, social and physical functioning, sexuality, identity and embodiment, sensory and memory-like experiences, and spirituality. Some changes were attributed by recipients to donor characteristics, whereas correspondences supported by independently obtained donor information were reported in a limited subset of studies. Proposed explanations ranged from psychological, pharmacological, physiological, and…
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