Focal point-by-point pulsed field ablation for the treatment of atrial arrhythmias in patients with challenging anatomy where radiofrequency ablation cannot be applied: A case series
Abstract
enables biphasic, monopolar F-PFA to be applied through commercially available contact force – sensing, solid-tip focal ablation catheters and visualized in the 3D electroanatomical mapping system (except for transient disappearance of the catheter during PFA delivery). PFA energy is delivered using a current of 22 A (7 pulse trains) for ablation of the posterior wall (ie, posterior portions of the pulmonary veins [PVs], posterior line of the posterior box) and a current of 25 A (10 pulse trains) for ablation of the anterior wall (anterior portions of the PVs, anterior lines, roof line of the posterior box). For ablation in the right atrium, a current of 22 A is used. Applications are guided by ablation tags of 6 mm placed with 20% – 30% overlap (inter-lesion distance of 4 mm), using a contact force between 10 and 25 g and an irrigation rate of 4 mL/min
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Chaos and quantum thermalization
- The Dalton quantum chemistry program system
- Cord Blood Leptin and Adiponectin as Predictors of Adiposity in Children at 3 Years of Age: A Prospective Cohort Study
- Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes
- Stable adiabatic quantum batteries
- A novel self-lipid antigen targets human T cells against CD1c(+) leukemias
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.