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Photon-Counting Computed Tomography for In-Stent Occlusion: Lumen Visualization and Myocardial Viability

Nguyen KV, Nguyen VT, Nguyen NT, Hoang Thi VH, Phung BN, Le Thi TL, Tran TQ, Tran TL et al.

JACC. Case reports, 2026

Abstract

Background: Conventional computed tomography evaluation of coronary stents is frequently limited by metal blooming artifacts. Ultra-high-resolution photon-counting detector computed tomography (PCCT) improves visualization of the internal vessel lumen and allows myocardial tissue characterization within a single noninvasive acquisition.

Case summary: A 58-year-old man with prior right coronary artery stenting presented with crescendo chest pain despite optimal therapy. Ultra-high-resolution PCCT demonstrated chronic total in-stent occlusion and robust left anterior descending artery-to-right coronary artery collaterals. Spectral iodine mapping identified a nonviable transmural scar, supporting conservative management and avoiding unnecessary high-risk revascularization.

Discussion: Recent studies report high concordance between PCCT and magnetic resonance imaging for late enhancement. This case interests readers by demonstrating PCCT's "one-stop-shop" capability to surpass traditional imaging barriers, providing the detailed evidence necessary to optimize high-stakes clinical decisions.

Take-home message: PCCT may improve diagnostic workflows and enhance precision for the management of complex coronary artery disease.

How strong is the evidence?

Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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