Successful sequential therapy for Stenotrophomonas maltophilia infection in a preterm neonate: a case report
Abstract
Background: A multidrug-resistant pathogen increasingly seen in newborn intensive care units, stenotrophomonas maltophilia presents treatment difficulties for preterm babies.
Case presentation: A 28-week preterm neonate developed S. maltophilia sepsis following prolonged mechanical ventilation. Initial therapy with trimethoprim- sulfamethoxazole (TMP-SMX) was ineffective, prompting a switch to levofloxacin, which led to clinical recovery and infection clearance.
Conclusion: This case highlights the need for tailored antimicrobial strategies in neonatal S. maltophilia infections. Sequential therapy with TMP-SMX and levofloxacin was effective, supporting the judicious use of fluoroquinolones in resistant cases.
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