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Case Series of Primary Esophageal Tuberculosis

Chen HM, Zhang SN, Tong J, Li CG, Gao MQ, Li Q

The American journal of tropical medicine and hygiene, 2026

Abstract

Gastrointestinal tuberculosis is a relatively common form of extrapulmonary tuberculosis. Primary esophageal tuberculosis is rare and frequently misdiagnosed or delayed in diagnosis by clinicians. Four cases of primary esophageal tuberculosis are reported. All patients involved underwent pathological examination of their esophageal lesions, which revealed granulomas. Additionally, molecular detection confirmed the presence of Mycobacterium tuberculosis DNA in two cases. All patients received antituberculosis therapy and achieved good outcomes.

How strong is the evidence?

Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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