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Managing Nasal Ischemia and Necrosis Post-Triamcinolone Injection: A New Case Series

Nazari S, Hadadian N, Bayatparidary F, Keyhan SO, Damsaz M, Fakih-Gomez N, Pourani MR

Case reports in otolaryngology, 2026

Abstract

Nasal ischemia following cosmetic injections has been reported in several cases. Postsurgery triamcinolone administration in the nasal region is a common practice to reduce inflammation and address pollybeak deformity. While cases of retinal artery occlusion following triamcinolone injection have been documented, this case series presents the first reported instance of nasal necrosis resulting from triamcinolone injection. This article explores the management strategies and therapeutic approaches for ischemia following triamcinolone administration. Four cases of nasal ischemia following triamcinolone injections administered postrhinoplasty are documented. The first case presented a young female who experienced ischemia with involvement of the columellar artery, leading to reduced blood flow in the dorsal and lateral nasal arteries. The remaining cases were patients who sought reconstructive surgery due to nasal necrosis caused by triamcinolone injections. Triamcinolone injection in the nasal region can lead to ischemia. Treatment options should be customized to each patient's condition. The THIS and FAT protocol with toxins (botulinum neurotoxin), high-dose hyaluronidase, and injectable platelet-rich fibrin (iPRF), solid platelet-rich fibrin (sPRF) dressings, and antibiotics as well as hyperbaric oxygen therapy (HBOT) can enhance tissue recovery, minimize scarring, and improve the overall outcome.

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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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