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Predicting Improvements in COPD with Clinically Important Improvements in Patient-Reported Outcomes: A Post Hoc Analysis of the EMAX Trial

C. Vogelmeier, E. Kerwin, I. Naya, L. Tombs, L. Bjermer, F. Maltais, P. Jones, D. Lipson et al.

2020

Abstract

1Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-Universität Marburg, Germany, Member of the German Center for Lung Research (DZL), Marburg, Germany; 2Clinical Research Institute of Southern Oregon, Medford, OR, USA; 3GSK, Brentford, Middlesex, UK (at the time of the study), RAMAX Ltd, Bramhall, Cheshire, UK; 4Precise Approach Ltd, contingent worker on assignment at GSK, Stockley Park West, Uxbridge, Middlesex, UK; 5Respiratory Medicine and Allergology, Lund University, Lund, Sweden; 6Centre de Pneumologie, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, QC, Canada; 7GSK, Brentford, Middlesex, UK; 8Respiratory Clinical Sciences, GSK, Collegeville, PA, USA and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

How strong is the evidence?

Evidence Hub reads this as a secondary / pooled analysis, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.

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