Analyzing the effects of a chemical peel on post‐inflammatory hyperpigmentation using line‐field confocal optical coherence tomography
Abstract
Line-field confocal optical coherence tomography (LC-OCT) is a burgeoning imaging device that allows for real-time, high-resolution, in vivo assessment of skin. 1,2 LC-OCT utilizes a laser to measure the backscattering of light from cellular structures. 3 LC-OCT can visualize upto500 µ matquasi-histologicalvertical(opticalcoherencetomogra-phy)andhorizontal(reflectanceconfocalmicroscopy)viewsoftheskin to produce a three-dimensional image. In comparison to traditional confocalmicroscopy,LC-OCTallowsgreaterdepthofvisualization,and faster image acquisition. 1,2 According to the 2020–2021 Aesthetic Plastic Surgery National Databank Statistics, chemical peels are one of the most extensively performed non-invasive cosmetic procedures in the United States. 4 Chemical peels can be used to treat photoaging, lentigines, melasma, and post-inflammatory hyperpigmentation. 5 Chemical peels cause controlled chemical injury leading to remodeling, regeneration, and wound healing. 6 We present a case study in which the patient presented to the clinic with complaints of hyperpigmented spots on his limb. To treat post-inflammatory hyperpigmentation, the patient underwent two treatment sessions of targeted spot treatment using a commercially blended chemical peel containing trichloroacetic acid and lactic acid, with a 1-month interval between sessions. LC-OCT was utilized for imaging before and after completion of two treatment sessions. Images were acquired in a protocol to obtain vertical,…
Read the paper
Related studies
- Characterization and Analysis of Porosity and Pore Structures
- Practical considerations for conducting ecotoxicity test methods with manufactured nanomaterials: what have we learnt so far?
- Dental Optical Coherence Tomography
- Radiation-shielding concrete: A review of materials, performance, and the impact of radiation on concrete properties
- Testing entanglement of annihilation photons
- Calanus finmarchicus seasonal cycle and diapause in relation to gene expression, physiology, and endogenous clocks
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.