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Neonatal Gonococcal Conjunctivitis Caused by Fluoroquinolone-Resistant Neisseria gonorrhoeae

Mizushima H, Komori M, Yoshida CA, Miyairi I

Emerging infectious diseases, 2025

Abstract

Prophylaxis for ophthalmia neonatorum remains in use despite decreased incidence of the condition. We report a breakthrough case of neonatal conjunctivitis in Japan caused by a levofloxacin-resistant Neisseria gonorrhoeae bacteria strain, co-infected with Chlamydia trachomatis bacteria. This case highlights failures in screening, prophylaxis, and treatment, underscoring the need to reassess prevention strategies.

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