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Association of Metformin use with risk of dementia in patients with type 2 diabetes: A systematic review and meta‐analysis

Chunbian Tang, Jiayi Hao, Fengran Tao, Qingguo Feng, Ying Song, Baoqi Zeng

Diabetes, obesity and metabolism, 2025

13 citations

Abstract

There is ongoing debate concerning the association of metformin with the risk of dementia in type 2 diabetes mellitus (T2DM). This study was conducted to evaluate the impact of metformin therapy on dementia in patients with T2DM.

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Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.

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