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Astatine-211 imaging by a Compton camera for targeted radiotherapy

Y. Nagao, M. Yamaguchi, Shigeki Watanabe, N. Ishioka, N. Kawachi, H. Watabe

Applied Radiation and Isotopes, 2018

23 citations

Abstract

Astatine-211 is a promising radionuclide for targeted radiotherapy. It is required to image the distribution of targeted radiotherapeutic agents in a patient's body for optimization of treatment strategies. We proposed to image 211At with high-energy photons to overcome some problems in conventional planar or single-photon emission computed tomography imaging. We performed an imaging experiment of a point-like 211At source using a Compton camera, and demonstrated the capability of imaging 211At with the high-energy photons for the first time.

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