Dosimetry for synchrotron x-ray microbeam radiation therapy
Abstract
In this work different dosimetric quantities of relevance for a new kind of radiation therapy, x-ray microbeam radiation therapy, have been both calculated and measured. A detailed analysis of the microbeam dose deposition produced by a single microbeam and by an array of microbeams has been performed using Monte Carlo simulations of the radiation transport. The peak-to-valley dose ratio was found to be decreasing with depth in the irradiated object. The dose in air (or more correctly the air kerma) produced by the high-flux synchrotron-generated x-ray beam was measured with a thimble-type ionization chamber in the uncollimated beam using two different approaches. The x-ray spectrum was measured with a powder diffraction method. The radiochromic film was found useful for rapid qualitative measurements of the dose distributions produced by the microbeams. The dose inside and near an x-ray microbeam was also measured with a MOSFET detector.
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