Safety and efficacy of robotic-assisted versus manual percutaneous coronary intervention: a systematic review and updated meta-analysis
Abstract
Percutaneous coronary intervention (PCI) is a fundamental aspect of coronary artery disease (CAD) management. However, manual PCI (M-PCI) procedures bring potential risks such as long-term radiation exposure, operator fatigue, and injuries, posing a threat of malignancies, orthopedic problems, cataracts, and other medical complications. The recently developed robotic-assisted PCI (R-PCI) system allows PCI to be performed from a protected cockpit, reducing radiation exposure, orthopedic injuries, and contrast media usage and improving stent placement accuracy for patients. This review aims to assess the safety and efficacy of robotic-assisted PCI. A comprehensive search was conducted across six databases including PubMed, EBSCO, Cochrane (CENTRAL), Scopus, ScienceDirect, and ProQuest, covering studies published from October 2023 to November 2023. The outcomes of interest included safety assessment through (I) procedure-related adverse event rate and (II) mortality rate, while efficacy was assessed through (I) procedural time, (II) fluoroscopy time, (III) contrast volume, (IV) clinical procedural success, and (V) technical success. Quality appraisal was performed using ROBINS-I, and meta-analysis was conducted using RevMan 5.4. A search across 6 databases resulted in 15 articles for analysis. We found that R-PCI is superior to M-PCI in reducing fluoroscopy time (MD = −3.68, 95% CI = −6.25 to −1.11, p = 0.005) and contrast volume (MD = −16.79, 95% CI = −22.28 to −11.30, p <…
How strong is the evidence?
Evidence Hub reads this as a meta-analysis. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
Read the paper
Related studies
- Ferulic acid regulates the AKT/GSK-3β/CRMP-2 signaling pathway in a middle cerebral artery occlusion animal model
- Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure–Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant Escherichia coli
- Photochemical behavior of levofloxacin
- Correlation Between Dissolution Profiles of Salt-Form Drugs in Biorelevant Bicarbonate Buffer and Oral Drug Absorption: Importance of Dose/ Fluid Volume Ratio
- Evaluation of the synergistic potential and mechanisms of action for de novo designed cationic antimicrobial peptides
- Synthesis of [11C]levofloxacin
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.