Feasibility, acceptability and prognostic value of muscle mass and strength measurement in patients with hip fracture: a systematic review
Abstract
We systematically reviewed whether muscle mass measurement was independently associated with adverse outcomes in patients with hip fracture. Our secondary aim was to systematically review whether muscle mass assessment was feasible and acceptable in this cohort. There are no studies specifically assessing feasibility and acceptability of muscle mass assessment in patients with hip fracture. Low muscle mass is associated with increased mortality, worse mobility and physical performance in unadjusted analyses. Included studies suggest muscle mass offers no additional prognostic benefit to muscle strength when assessing sarcopenia in acute hip fracture. Sarcopenia is diagnosed on the basis of low muscle strength, with low muscle mass used to confirm diagnosis. The added value of measuring muscle mass is unclear. We undertook a systematic review to assess whether muscle mass measurement in patients with hip fracture was acceptable, feasible and independently associated with adverse outcomes. Electronic databases (MEDLINE, EMBASE, CENTRAL, CINAHL, Clinicaltrials.gov) were searched for studies of patients with hip fracture aged ≥ 60 with perioperative muscle mass or strength assessments. Associations with postoperative outcomes including death, length of stay and activities of daily living were extracted. Risk-of-bias was assessed using the AXIS and ROBINS-I tools. Due to the degree of study heterogeneity, data were analysed by narrative synthesis. The search strategy identified…
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Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 7,860 participants or records.
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