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Comparative Clinical Outcomes of Divide and Conquer and Tilt and Tumble Cataract Surgery: A Randomized Controlled Trial

Johan Ursberg, Andreas Viberg, Madeleine Zetterberg

Clinical Ophthalmology, 2026

535 participants

Abstract

Purpose To compare the clinical performance of the divide and conquer and tilt and tumble techniques in cataract surgery with respect to surgical efficiency, safety and energy usage. Setting The research was conducted at two private clinics specialized in cataract surgeries located in the southern region of Sweden. Design The study was a prospective randomized controlled trial. Methods A total of 535 patients undergoing cataract surgery were randomized to either divide and conquer or tilt and tumble. Primary outcomes included total surgery time, phacoemulsification time, ultrasound time, cumulative dissipated energy (CDE) and intraoperative complications. Postoperative visual acuity, intraocular pressure (IOP) and, for a subset, central retinal thickness (CRT), were assessed at follow up. Results Tilt and tumble demonstrated significantly shorter operation time, 4.68 compared to 6.50 minutes (p<0.001), phaco time 60 versus 148 seconds (p<0.001) and ultrasound time, 32 versus 40 seconds (p<0.001) compared to divide and conquer. Baseline characteristics, Energy expenditure (CDE), intraoperative complications and postoperative outcomes did not differ significantly between groups. Conclusion Our results revealed that the tilt and tumble technique is notably swifter and demonstrates comparable safety, energy consumption and postoperative outcome compared to divide and conquer. This sheds light on the potential benefits of the tilt and tumble technique ultimately enhancing patient…

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 535 participants or records.

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