Long-term effects of oral nutritional supplement with hmb on clinical and nutritional outcomes in community-dwelling older adults at risk of malnutrition: a randomized, placebo-controlled trial
Abstract
s Clinical Nutrition ESPEN 54 (2023) 463e726 standard care after hospital discharge, 2)to determine the prevalence of PEM according to the Global Leadership Initiative on Malnutrition (GLIM) criteria after discharge, 3)to investigate if six-months NCP therapy impacts hospital readmission and/or length of stay. Methods: The HOMEFOOD study is a six-month randomized controlled intervention. Total participants were 104 patients, aged 65 years at risk for malnutrition or malnourished according to nutritional screening and discharged home. Dietary intake at baseline, and at six months after discharge was assessed using a 24-hour-dietary-recall interview. The prevalence of PEM was determined according to GLIM criteria at baseline and after 6 months. Data on hospital readmissions and length of stay among participants were obtained. Results: Energy and protein intake six months after hospital discharge were significantly higher in the intervention group (p<0.001). At baseline 58% patients in the control group and 65% patients in the intervention group were malnourished according to GLIM criteria. However, six months after discharge, 17% were malnourished in the intervention group according to GLIM criteria, 73% in the control group. Six-month NCP therapy did not have any impact on hospital readmission and/or length of stay. Conclusion: Six-month NCP therapy impacts energyand protein intake and decrease risk of malnourishment according to GLIM criteria. However, six-month NCP therapy…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 104 participants or records.
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