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"A Mini-Review on Conjugated Polymer-Based Fluorescence Probes for Bilirubin Detection"

Thangaraj Senthilkumar

Biomedical Journal of Scientific & Technical Research, 2022

Abstract

This review report provides information on the specific conjugated polymer (CP)-based fluorescence probes for bilirubin detection.Few CPs are available, used to detect bilirubin at the nano level.These polymers are soluble in the aqueous phase, appropriate for detecting bilirubin.The sensing efficiency of the CP is demonstrated by the fluorescence resonance energy transfer (FRET) emission and quenching of the polymer fluorescence.DLS provides the particle size of polymer and interaction between the polymer and bilirubin shown by ITC.The different developed CP by the researcher can detect the bilirubin in an aqueous medium and human serum, despite other biomolecules and metal ions with the limit of detection (LOD) of up to 6.9 pM.

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