Headache in a case of tuberculosis: think beyond meningitis-a case report
Abstract
Background: Intracranial hypertension may be idiopathic (IIH) or due to some underlying causes, such as an intracranial space-occupying lesion or drug induced.
Case presentation: A 14-year-old South Asian male was being treated for MDR-TB with anti-tubercular therapy (including levofloxacin) when he developed a headache lasting 8 days. Examination revealed bilateral papilledema. The CSF study was unremarkable. MRI revealed left transverse and sigmoid sinus stenosis. A probable diagnosis of levofloxacin-induced intracranial hypertension was made, and the drug was stopped. The symptoms resolved within 1 week of drug cessation, and the papilledema resolved within 2 weeks.
Conclusions: Although rare, clinicians must be aware of this side effect of levofloxacin while evaluating a case with recent onset of features of raised ICP and taking this drug as part of some therapy.
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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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