Evidence Hub

Detection of the ovarian cancer biomarker CA-125 using chemiluminescence resonance energy transfer to graphene quantum dots

Israa Ali Zaidan Al-Ogaidi, Honglei Gou, Zoraida P. Aguilar, Shouwu Guo, Alice K. Melconian, Abdul Kareem A. AL-Kazaz, Fanke Meng, Nianqiang Wu

Chemical Communications, 2013

166 citations

Abstract

An immunoassay has been developed for the detection of the ovarian cancer biomarker CA-125 by utilizing the chemiluminescence resonance energy transfer to graphene quantum dots. This biosensor shows a wide linear range from 0.1 U mL(-1) to 600 U mL(-1) with a limit of detection of 0.05 U mL(-1) for CA-125 in a buffer solution.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free