Effect of oat consumption on blood pressure: a systematic review and meta-analysis of randomized controlled trials
Abstract
BACKGROUND
Current clinical trials have shown controversial results regarding the effects of oat consumption on blood pressure (BP) in adults.
OBJECTIVE
The meta-analysis was conducted to systematically evaluate the effects of oat consumption on BP in adults.
METHODS
Electronic databases including PubMed, Web of Science, Scopus, the Cochrane Library, and Embase were searched until December 13, 2021 for eligible randomized controlled trials (RCTs). RCTs that published in English and explored the effects of oat consumption on BP in adults under matched total energy intake were included. Meta-analysis using a random-effects model was performed. The pooled effect size was expressed as mean difference (MD) and 95% confidence interval (CI). I2 statistics were used to quantify heterogeneity. The risk of bias was assessed using the Cochrane Risk-of-Bias tool (RoB 2.0).
RESULTS
21 RCTs involving 1569 participants were included. The pooled results indicated that consuming oats significantly reduced systolic blood pressure (SBP) [MD = -2.82 mmHg; (95% CI -4.72, -0.93); P = 0.004]. Subgroup analyses indicated that oat consumption significantly reduced SBP in hypertensive participants, or when compared to control group participants who consumed refined grains. No significant reduction in diastolic blood pressure (DBP) after oat consumption was observed [MD = -1.16 mmHg; (95% CI -2.37, 0.04); P = 0.060]. However, the sensitivity analysis of DBP, removal of individual studies or "leave one…
How strong is the evidence?
Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 1,569 participants or records.
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