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Metformin adherence and discontinuation among patients with type 2 diabetes: A retrospective cohort study

Yue-Xin Tang, Tracey Weiss, Ji-Nan Liu, S. Rajpathak, K. Khunti

Journal of Clinical & Translational Endocrinology, 2020

26 citations

Abstract

Highlights • Poor adherence to therapy for T2DM is associated with lower reductions in HbA1c.• About one-third of patients initiating metformin discontinued within 12 months.• Fewer than 50% of all patients were adherent to metformin.

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.

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