Metformin and Risk of Alzheimer’s Disease Among Community-Dwelling People With Diabetes: A National Case-Control Study
Abstract
Contrary to 2 previous studies, this carefully designed case-control study, which used the entire population of Finland, metformin was not associated with an increased risk of developing an Alzheimer’s disease. Instead, long-term use of higher doses of metformin was associated with a decreased odds of Alzheimer's disease.
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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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