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Paracetamol, NSAIDS and opioid analgesics for chronic low back pain: a network meta-analysis

Matthew K. Bagg, A. McLachlan, Christopher G. Maher, Steven J. Kamper, C. Williams, N. Henschke, B. Wand, G. Moseley et al.

Cochrane Database of Systematic Reviews, 2018

26 citations

Abstract

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

To answer the clinical question: ‘what analgesic medicine shall I prescribe this patient with chronic low back pain to reduce their pain?’.

The objectives are to determine the analgesic effects, safety, effect on function, and relative rank according to analgesic effect, safety and effect on function of a single course of opioid analgesics, NSAIDs or paracetamol or combinations of these medicines.

How strong is the evidence?

Evidence Hub reads this as a meta-analysis. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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