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Minimally Invasive Spinal Interventions for Back and Neck Pain in the Pediatric Population: a Systematic Review

Jevotovsky D, Dovlatyan R, Mermelstein S, Banks D, Medina R, Dukat A, Lee C, Hirani S et al.

Current pain and headache reports, 2026

258 participants

Abstract

Objective: To evaluate the effectiveness and safety of spinal interventions for pediatric patients with chronic back and neck pain who failed conservative management.

Design: Systematic review.

Methods: Following PRISMA 2020 guidelines, a comprehensive search of PubMed, Embase, Web of Science, and Cochrane Central was performed through August 2024. Eligible studies included clinical reports of interventional procedures for pediatric spine related pain. Primary outcomes were pain reduction measured by subjective scales or validated instruments; secondary outcomes included safety and adverse events. Risk of bias and certainty of evidence were assessed using the MASTER and GRADE scales.

Results: Of 578 identified studies, 8 met inclusion criteria, encompassing 258 pediatric patients. Interventions included epidural steroid injections (n = 227), sacroiliac joint injections (n = 13), facet injections (n = 2), ozone discolysis (n = 2), medial branch blocks (n = 1), interspinous ligament injections (n = 1), and microdiscectomy (n = 1). Across all studies, some degree of pain relief was reported, with functional improvement noted when measured. Adverse events were rare, mild, and transient, including a post-procedural headache and a transient sciatic motor block. No major long-term complications were reported. Evidence certainty was graded as 'very low' due to small sample sizes, observational designs, and heterogeneous methodologies.

Conclusions: Preliminary evidence suggests…

How strong is the evidence?

Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 258 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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