Comparison of posterior transversus abdominis plane block and erector spinae plane block for postoperative analgesia after caesarean section performed under spinal anesthesia: a prospective randomized trial
Abstract
Background: This study aimed to compare the analgesic efficacy of the transversus abdominis plane block (TAPB) and the erector spinae plane block (ESPB) following cesarean delivery under spinal anesthesia. The primary endpoint was the proportion of patients requiring rescue analgesia within the first 24 hours postoperatively. Secondary outcomes included time to first rescue analgesia, Numerical Rating Scale (NRS) scores at predefined time points (30 minutes, 4, 8, 12, 16, and 24 hours), and the incidence of persistent postsurgical pain at two months.
Methods: This single-center, prospective, randomized controlled study included patients undergoing cesarean section under spinal anesthesia. Participants were randomly allocated into two groups: TAPB and ESPB. Postoperative pain and vital signs were assessed 30 minutes after block application and at 4, 8, 12, 16, and 24 hours postoperatively. Pain intensity was measured using the NRS (0=no pain, 10=worst imaginable pain). Rescue analgesia was administered when the NRS score was ≥4. Diclofenac sodium 75 mg intramuscularly (IM) was given for NRS scores of 4-5, while intravenous (IV) morphine sulfate 0.05 mg/kg was administered for NRS scores ≥6.
Results: A total of 94 patients were analyzed: 48 received ESPB and 46 received TAPB postoperatively. The TAPB group had a significantly higher proportion of patients requiring rescue nonsteroidal anti-inflammatory drug (NSAID) analgesics compared to the ESPB group (58.70% vs. 27.08%,…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 94 participants or records.
Read the paper
Related studies
- Effect of dexamethasone as an analgesic adjuvant to multimodal pain treatment after total knee arthroplasty: randomised clinical trial
- Effect of a Postoperative Multimodal Opioid-Sparing Protocol vs Standard Opioid Prescribing on Postoperative Opioid Consumption After Knee or Shoulder Arthroscopy: A Randomized Clinical Trial
- Comparison of the Post-Caesarean Analgesic Effect of Adding Dexmedetomidine to Paracetamol and Ketorolac: A Randomized Clinical Trial
- A triple-blind randomized clinical trial of different associations between dexamethasone and non-steroids anti-inflammatories for preemptive action in third molar extractions
- An open label randomized clinical trial of Indomethacin for mild and moderate hospitalised Covid-19 patients
- Oral paracetamol and/or ibuprofen for treating pain after soft tissue injuries: Single centre double-blind, randomised controlled clinical trial
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.