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The effect of the anti‐diabetic drug metformin on musculoskeletal pain: A cross‐sectional study with 21,889 individuals from the UK biobank

A. P. Carvalho‐e‐Silva, A. Harmer, M. Ferreira, P. Ferreira

European Journal of Pain, 2021

23 citations

Abstract

Although there is growing evidence of metformin's pleiotropic effects, including possible effects on pain, there is a lack of studies investigating the association of metformin with the prevalence of musculoskeletal pain among a large cohort with type 2 diabetes cohort.

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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