Clomiphene citrate alone versus combined metformin and clomiphene citrate versus combined metformin and clomiphene citrate and drilling versus metformin alone in infertile Indian women with PCOS: a prospective cross-sectional study
Abstract
Polycystic ovary syndrome (PCOS) is a common cause of infertility and is associated with chronic anovulation and hyperandrogenemia. It affects up to 6% of women with reproductive age. Clomiphene citrate remains the firstline therapy for induction of ovulation in these women. Clomiphene resistance (i.e., failure to ovulate after receiving 150 mg/day) remains a common problem and occurs in approximately 15%–40% in women with PCOS. ABSTRACT
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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