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Meta‐Analysis of Thermal Versus Pulse Field Ablation for Pulmonary Vein Isolation Durability in Atrial Fibrillation: Insights From Repeat Ablation

Jin-Cheng Chen, Yin-jun Mao, Qun-ying Huang, Zheng-Ai Cheng, Shaobin He, Qiu-Xia Xu, Yin Zhang

Clinical Cardiology, 2025

11 citations

Abstract

Pulsed field ablation (PFA) represents an innovative technique for pulmonary vein isolation (PVI), exhibiting promising efficacy and safety in initial clinical studies. However, the long‐term durability of PVI and reconnection patterns following PFA are not as well‐characterized compared to those associated with thermal energy sources such as cryoballoon ablation (CBA) or radiofrequency ablation (RFA). The objective of this study is to compare the durability of lesions resulting from repeat ablation after index PVI using PFA versus thermal ablation (TA).

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Evidence Hub reads this as a meta-analysis. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.

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