Potential Use of Umbilical Cord Mesenchymal Stem Cells and Secretoms for Infertility Therapy in Polycystic Ovary Syndrome (PCOS) Patients With Insulin Resistance
Abstract
The purpose of this study is to investigating the effect of Umbilical Cord Mesenchymal Stem Cell (UC-MSCs) and secretomes to insulin resistance in Polycystic Ovary Syndrome (PCOS) patients. This study has 4 arms namely UC-MSCs treatment, secretomes treatment, UC-MSCs and secretomes treatment, and control.
Conditions: Polycystic Ovary Syndrome.
Primary outcome: Blood serum sample; Free Androgen index (FAI); Insulin, Glucose Plasma, and Insulin Resistance; Sex Hormone Binding Globulin (SHBG) and Anti-Mullerian Hormone (AMH); Leptin and Adiponectine Profile; TNFα, IL-1 β, IL-6, IL-10 Profile.
Enrollment: 44 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 44 participants or records.
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