Metformin in Polycystic Ovary Syndrome Patients
Abstract
Objective: To determine the effect of metformin on the clinical presentation and metabolic disturbances of polycystic ovary syndrome. Study Design: Observational study. Place and Duration of Study: This study was conducted at the Department of Obstetrics and Gyneacology Unit-I, Sandeman Provincial Hospital, Bolan Medical College, Quetta from 09-09-2018 to 06-06-2019 Materials and Methods: Fifty patients with clinical signs and symptoms of polycystic ovaries syndrome attending the OPD of department of obstetrics and gyneacology Unit-I, Sandeman provincial hospital, Bolan medical college Quetta. Results: A total of fifty women with Polycystic Ovary Syndrome were included in the study. The average age of the patients was found 26.46 + 1.40 (95% CI: 23.64 to 29.28) years. The signs and symptoms, of Acne was present in 33 patients (66 %), Hirsutism was present in 43 patients (86 %), Menstrual Irregularity was present in all patients (100 %), Obesity was present in 28 patients (56 %) and Infertility was present in 37 patients (74 %), were present in the patients before treatment. Improvement in the signs and symptoms, of Acne was seen in 2 patients (6.06 %), Hirsutism was seen in 2 patients (4.65 %), Menstrual Irregularity was seen in 13 patients (26 %), Obesity was seen in 4 patients (5.40 %) and Infertility was seen in 2 patients (5.40 %), after 3 months’ treatment. Improvement in the signs and symptoms, of Acne was seen in 5 patients (15.15 %), Hirsutism was seen in 6 patients…
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