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Impact of Yoga and Naturopathy in a Patient with Chronic Idiopathic Axonal Polyneuropathy Associated with Metabolic Syndrome and Rheumatoid Arthritis: A Case Report

Sathiyavathi G, Vijay A, Keerthi P, Suganthi S, Mooventhan A, Manavalan N

Advances in mind-body medicine, 2026

100 participants

Abstract

Background: Chronic idiopathic axonal polyneuropathy (CIAP) is a slowly progressive nerve disorder characterized by sensory or sensorimotor dysfunction, which is linked to type 2 diabetes mellitus, hypertension, and metabolic syndrome. CIAP affects 75 to 125 per 100 000 people, with prevalence increasing in individuals over 60 years old.

Case study: A 53-year-old female homemaker presented to our inpatient facility with complaints of chronic pain, burning sensation, and discoloration over both lower limbs, accompanied by numbness persisting for the past 10 years and a 15-year history of rheumatoid arthritis (RA). Despite adherence to the prescribed conventional treatment regimen (Metformin, Atorvastatin, Amlodipine, Rabeprazole sodium, Domperidone, Gabapentin, Nortriptyline hydrochloride, and Tramadol), as verified from her medical records, the patient's symptoms did not improve.

Intervention: The patient was provided with an integrative care for one month at our yoga and naturopathy (YN) hospital, where she received a structured lifestyle intervention comprising daily yoga sessions, a calorie-restricted plant-based diet, and adjunct naturopathic therapies such as massage, hydrotherapy, mud therapy, heliotherapy, and acupuncture with reflexology.

Results: Post-intervention assessments showed notable improvements in anthropometric measurements, inflammatory markers, lipid profile, the impact of RA on disease scores, complete blood counts, and quality of life.

Conclusion: The…

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 100 participants or records.

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