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Ignavigranum ruoffiae isolated from a scrotal abscess: a case report and literature review

Zhang K, Zhu S, Zhang M, Li H, Xu Y, Zhao P, Wang Z

BMC infectious diseases, 2026

Abstract

Background: Ignavigranum ruoffiae is a rare catalase-negative, facultatively anaerobic Gram-positive coccus. Published human infections remain exceptionally uncommon and have mainly involved localized suppurative disease outside the genitourinary tract. Scrotal involvement has not, to our knowledge, been described previously in the available literature.

Case report: A 63-year-old man presented with a 2-day history of progressive painful swelling of the left scrotum and inguinal region. Systemic inflammatory findings were not striking on admission, with a white blood cell count of 9.27 × 10^9/L and a procalcitonin level of 0.08 ng/mL. Urinalysis was unremarkable, and urine culture showed no bacterial growth. Scrotal ultrasonography demonstrated a 21 × 12 × 18 mm heterogeneous lesion in the left inguinal-scrotal region, with peripheral strip-like blood-flow signals and no documented internal vascularity. Empirical intravenous levofloxacin was started after admission. On hospital day 2, the patient developed a transient fever of 38.0 °C, and the lesion ruptured spontaneously. Needle aspiration drainage yielded approximately 5 mL of gray-white pus. Culture of aspirated pus showed pure growth of small gray-white colonies after 48 h under aerobic conditions with 5% CO2; anaerobic culture recovered no additional anaerobic organisms. The isolate was identified as I. ruoffiae by MALDI-TOF MS using a Bruker microflex LT/SH system with Biotyper software version 4.1.100 and database…

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